display: table-cell如果您不关心IE7，我会使用@sandeep的答案。
否则，这是一个替代方案，但有一个缺点：“正确” div必须在HTML中排在首位。
#parent {
overflow: hidden;
border: 1px solid red
}
.right {
float: right;
width: 100px;
height: 100px;
background: #888;
}
.left {
overflow: hidden;
height: 100px;
background: #ccc
}
<div id="parent">
<div class="right">right</div>
<div class="left">Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nullam semper porta sem, at ultrices ante interdum at. Donec condimentum euismod consequat. Ut viverra lorem pretium nisi malesuada a vehicula urna aliquet. Proin at ante nec neque commodo bibendum. Cras bibendum egestas lacus, nec ullamcorper augue varius eget.</div>
</div>
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